Best Laboratory Practice for Primary Aldosteronism and Related Condition
About the Speaker:
Dr. Daniel Holmes earned his undergraduate degree in Chemical Physics from the University of Toronto. He went to medical school at the University of British where he also did his residency in Medical Biochemistry. He is a Clinical Professor of Pathology and Laboratory Medicine at UBC and Head and Medical Director of the Department of Pathology and Laboratory Medicine at St
Paul's Hospital in Vancouver and Interim Medical Director of the British Columbia Provincial Toxicology Laboratory. Interests include clinical endocrinology with a focus on secondary hypertension. lipidology, clinical mass spectrometry, and data science in application to data automation, visualization and clinical utilization.
Moderator: Li Wang, MSc, MD, FRCPC. Columbia(UBC)
Clinical Associate Professor. Department of Pathology and Laboratory Medicine, University of British Columbia.
Primary Aldosteronism (PA) is by far the most common form of secondary hypertension representing about 10% of hypertension in all comers. However. screening, diagnosis and subtype classification of PA are highly dependent on laboratory medicine providing reporting that is clear and directive.
The existence of methodological biases for aldosterone/renin, the multiple means to assess renin, the confusing variety of commonly employed units of reporting, and the failure of clinical guidelines to acknowledge these challenges make the process of case identification challenging for physicians. Further, a typical internist may only order the testing a few times per year whereas a laboratory may see hundreds to thousands of screening/diagnostic events per year. This places the laboratory in a unique position to accrue a level of experience that may be impossible for a typical clinician to achieve.
In this session we will highlight the challenges and opportunities for laboratorians to play a pivotal role in the diagnosis and cure of this common and often curable form of secondary hypertension.